Triciribine

1 mg

Cat. No.: 32-M26

$109.00

Triciribine is a synthetic cell-permeable and reversible tricyclic nucleoside that selectively inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3 but does not inhibit Akt kinase activity or upstream Akt activators, PI3-Kinase or PDK1. It has shown to inhitib cell growth and induce apoptosis in cancer cells with aberrant Akt activity both in vitro and in vivo.

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Details

TECHNICAL INFORMATION

Other Names1,​5-​dihydro-​5-​methyl-​1-​β-​D-​ribofuranosyl-​1,​2,​5,​6,​8-​pentaazaacenaphthylen-​3-​amine

Chemical Formula: C13H16N6O4

CAS Number: 35943-35-2

Molecular Weight: 320.3

Purity:  >98%

Appearance: crystalline solid

Solubility: DMSO

 

STORAGE AND HANDLING

Storage: Store at -4°C and protected from light.

Stability: Stock solutions stable at -20°C for up to 2 years.

Shipping Conditions: Shipped at room temperature.

 

PRODUCT USE

Soluble in DMSO. Soluble at >25mg/ml.