Reversine

2 mg

Cat. No.: 18-S41

$84.00

Reversine is a potent, selective A3 adenosine receptor antagonist. It has been shown to induce differentiated myogenic-linage committed cells to become multipotent mesenchymal progenitor cells.

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TECHNICAL INFORMATION

 Other Names: N6-​cyclohexyl-​N2-​[4-​(4-​morpholinyl)phenyl]-​1H-​purine-​2,​6-​diamine

Chemical Formula: C21H27N7O

CAS Number: 656820-32-5

Molecular Weight: 393.5

Purity:  >98% by HPLC

Appearance: Crystalline solid

Solubility: DMSO

 

STORAGE AND HANDLING

Storage: Store at 4°C and protected from light. Following reconstitution, store  aliquots at -20°C. 

Stability: Stock solutions stable at -20°C for up to 2 years.

Shipping Conditions: Shipped at room temperature.

 

PRODUCT USE

Soluble in DMSO. Soluble at 7mg/ml. Incubate in a 37°C water bath for 5 minutes if precipitate is observed.

 

References

Santaguida et al. (2010) Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor Reversine. J Cell Biol. 190: 73-87.

McMillin et al.  (2010). Tumor cell specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity. Nat Med. 16: 483-489.

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